About the Authors

James L Hougland

Affiliation Department of Chemistry, University of Chicago, Illinois, United States of America

Alexander V Kravchuk

Affiliation Department of Biochemistry, Stanford University, California, United States of America

Daniel Herschlag

To whom correspondence should be addressed. E-mail: herschla@cmgm.stanford.edu (DH), Email: jpicciri@uchicago.edu (JP)

Affiliation Department of Biochemistry, Stanford University, California, United States of America

Joseph A Piccirilli

To whom correspondence should be addressed. E-mail: herschla@cmgm.stanford.edu (DH), Email: jpicciri@uchicago.edu (JP)

Affiliations Department of Chemistry, University of Chicago, Illinois, United States of America, Department of Biochemistry and Molecular Biology, University of Chicago, Illinois, United States of America, Howard Hughes Medical Institute, University of Chicago, Illinois, United States of America

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

JLH, AVK, DH, and JAP conceived and designed the experiments. JLH performed the experiments and analyzed the data. JLH and AVK contributed reagents/materials/analysis tools. JLH, DH, and JAP wrote the paper.