About the Authors

Klaus Förstemann, Yukihide Tomari, Tingting Du, Phillip D Zamore
Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Vasily V Vagin
Institute of Molecular Genetics of RAS, Moscow, Russia

Ahmet M Denli
Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Diana P Bratu, Carla Klattenhoff, William E Theurkauf
Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Corresponding Author

phillip.zamore@umassmed.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

KF, YT, TD, VVV, WET, and PDZ conceived and designed the experiments. KF, YT, TD, VVV, DPB, CK, and WET performed the experiments. KF, YT, TD, VVV, DPB, CK, WET, and PDZ analyzed the data. KF, YT, TD, VVV, AMD, DPB, CK, WET, and PDZ contributed reagents/materials/analysis tools. KF, WET, YT, and PDZ wrote the paper.