About the Authors

Rasmus Nielsen

To whom correspondence should be addressed. E-mail: rasmus@binf.ku.dk

Affiliations Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America, Center for Bioinformatics, University of Copenhagen, Denmark

Carlos Bustamante

Affiliation Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

Andrew G Clark

Affiliation Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

Stephen Glanowski

Affiliation Applied Biosystems, Rockville, Maryland, United States of America

Timothy B Sackton

Affiliation Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

Melissa J Hubisz

Affiliation Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

Adi Fledel-Alon

Affiliation Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

David M Tanenbaum

Affiliation Celera Genomics, Rockville, Maryland, United States of America

Daniel Civello

Affiliation Celera Diagnostics, Alameda, California, United States of America

Thomas J White

Affiliation Celera Diagnostics, Alameda, California, United States of America

John J. Sninsky

Affiliation Celera Diagnostics, Alameda, California, United States of America

Mark D Adams

Address ¤ Current address: Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America

Affiliation Celera Genomics, Rockville, Maryland, United States of America

Michele Cargill

Affiliation Celera Diagnostics, Alameda, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SG, DMT, DC, TJW, JJS, MDA, and MC conceived and designed the experiments and performed the experiments. RN, CB, AGC, TBS, MJH, and AFA analyzed the data and contributed reagents/materials/analysis tools. RN, CB, AGC, MDA, and MC wrote the paper.