About the Authors

Masahiro Tanaka

Affiliation Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, United States of America

Raynard Bateman

Affiliation Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, United States of America

Daniel Rauh

Affiliation Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, United States of America

Eugeni Vaisberg

Affiliation Cytokinetics Inc., South San Francisco, California, United States of America

Shyam Ramachandani

Affiliation Cytokinetics Inc., South San Francisco, California, United States of America

Chao Zhang

Affiliation Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, United States of America

Kirk C Hansen

Affiliation Department of Pharmaceutical Chemistry, Mass Spectrometry Facility, University of California, San Francisco, California, United States of America

Alma L Burlingame

Affiliation Department of Pharmaceutical Chemistry, Mass Spectrometry Facility, University of California, San Francisco, California, United States of America

Jay K Trautman

Affiliation Cytokinetics Inc., South San Francisco, California, United States of America

Kevan M Shokat

To whom correspondence should be addressed. E-mail: shokat@cmp.ucsf.edu

Affiliation Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, United States of America

Cynthia L Adams

Affiliation Cytokinetics Inc., South San Francisco, California, United States of America

Competing Interests

EV, SR, JKT, and CLA are affiliated with/employed by Cytokinetics.

Author Contributions

MT, RB, DR, CLA, and KS conceived and designed the experiments. MT, RB, DR, SR, KCH, and CLA performed the experiments. MT, RB, DR, EV, and CLA analyzed the data. CZ, ALB, and JKT contributed reagents/materials/analysis tools. KS wrote the paper.