Cobalamin-Independent Methionine Synthase (MetE): A Face-to-Face Double Barrel That Evolved by Gene Duplication

Robert Pejchal; Martha L Ludwig

doi:10.1371/journal.pbio.0030031

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Peer-reviewed

Research Article

Cobalamin-Independent Methionine Synthase (MetE): A Face-to-Face Double Barrel That Evolved by Gene Duplication

Robert Pejchal,

Affiliation Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Martha L Ludwig

*To whom correspondence should be addressed. E-mail: mlludwig@umich.edu

Affiliations Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, United States of America, Biophysics Research Division, University of Michigan, Ann Arbor, Michigan, United States of America
⨯

Cobalamin-Independent Methionine Synthase (MetE): A Face-to-Face Double Barrel That Evolved by Gene Duplication

Robert Pejchal,
Martha L Ludwig

Published: December 28, 2004
https://doi.org/10.1371/journal.pbio.0030031

About the Authors

Robert Pejchal

Affiliation Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, United States of America

Martha L Ludwig

*To whom correspondence should be addressed. E-mail: mlludwig@umich.edu

Affiliations Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, United States of America, Biophysics Research Division, University of Michigan, Ann Arbor, Michigan, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

RP and MLL conceived and designed the experiments. RP performed the experiments. RP analyzed the data. RP contributed reagents/materials/analysis tools. RP and MLL wrote the paper.

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Zinc
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Glutamate
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Sulfur
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Enzyme structure
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Cysteine
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Methionine
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Gene duplication
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Methyltransferases
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