About the Authors
- Vardhman K Rakyan
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Affiliation The Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom
- Thomas Hildmann
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Affiliation Epigenomics AG, Berlin, Germany
- Karen L Novik
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address: Cancer Genetics Group, Genome Sciences Centre, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada
Affiliation The Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom
- Jörn Lewin
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Affiliation Epigenomics AG, Berlin, Germany
- Jörg Tost
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Affiliation Centre National de Génotypage, Evry Cedex, France
- Antony V Cox
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Affiliation The Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom
- T. Dan Andrews
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Affiliation The Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom
- Kevin L Howe
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Affiliation The Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom
- Thomas Otto
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Affiliation Epigenomics AG, Berlin, Germany
- Alexander Olek
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Affiliation Epigenomics AG, Berlin, Germany
- Judith Fischer
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Affiliation Centre National de Génotypage, Evry Cedex, France
- Ivo G Gut
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Affiliation Centre National de Génotypage, Evry Cedex, France
- Kurt Berlin
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Affiliation Epigenomics AG, Berlin, Germany
- Stephan Beck
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*To whom correspondence should be addressed. E-mail: beck@sanger.ac.uk
Affiliation The Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom
Competing Interests
JL, KB, TH, TO, and AO are employees of Epigenomics AG. IGG and SB are members of the scientific advisory board of Epigenomics AG, but do not benefit financially from their involvement in this study. Epigenomics AG has filed for patents based on some of the work described here. Epigenomics AG was a scientific collaborator in the study. The work described here was funded by a grant from the European Union Framework 5 Programme.
Author Contributions
VKR, TH, KLN, AO, SB, KB, and IGG conceived and designed the experiments. VKR, KLN, JL, and JT performed the experiments. VKR, TH, KLN, JL, DA, KLH, AVC, SB, JT, KB, and IGG analyzed the data. VKR, JL, TO, DA, KH, and AVC contributed reagents/materials/analysis tools. VKR and SB wrote the paper.