About the Authors

Ulrike S Eggert

To whom correspondence should be addressed. E-mail: ulrike_eggert@hms.harvard.edu

Affiliations Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Institute of Chemistry and Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

Amy A Kiger

Affiliation Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Constance Richter

Affiliation Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

Zachary E Perlman

Affiliations Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Institute of Chemistry and Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

Norbert Perrimon

Affiliations Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Timothy J Mitchison

Affiliations Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Institute of Chemistry and Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

Christine M Field

Affiliation Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

USE, AAK, NP, TJM, and CMF conceived and designed the experiments. USE, AAK, and CR performed the experiments. USE, AAK, and CR analyzed the data. USE, AAK, CR, ZEP, and CMF contributed reagents/materials/ analysis tools. USE, AAK, TJM, and CMF wrote the paper.