About the Authors

Naomi Ward

To whom correspondence should be addressed. E-mail: nward@tigr.org

Affiliations The Institute for Genomic Research, Rockville, Maryland, United States of America, Center of Marine Biotechnology, Baltimore, Maryland, United States of America

Øivind Larsen

Affiliation Department of Biology, University of Bergen, Bergen, Norway

James Sakwa

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Live Bruseth

Affiliation Department of Molecular Biology, University of Bergen, Bergen, Norway

Hoda Khouri

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

A. Scott Durkin

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

George Dimitrov

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Lingxia Jiang

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

David Scanlan

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Katherine H Kang

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Matt Lewis

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Karen E Nelson

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Barbara Methé

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Martin Wu

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

John F Heidelberg

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Ian T Paulsen

Affiliations The Institute for Genomic Research, Rockville, Maryland, United States of America, Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America

Derrick Fouts

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Jacques Ravel

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Hervé Tettelin

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Qinghu Ren

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Tim Read

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Robert T DeBoy

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Rekha Seshadri

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Steven L Salzberg

Affiliations The Institute for Genomic Research, Rockville, Maryland, United States of America, Department of Computer Science, Johns Hopkins University, Baltimore, Maryland, United States of America

Harald B Jensen

Affiliation Department of Molecular Biology, University of Bergen, Bergen, Norway

Nils Kåre Birkeland

Affiliation Department of Biology, University of Bergen, Bergen, Norway

William C Nelson

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Robert J Dodson

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Svenn H Grindhaug

Affiliation Department of Informatics, University of Bergen, Bergen, Norway

Ingeborg Holt

Affiliation National Institutes of Health, National Human Genome Research Institute, Bethesda, Maryland, United States of America

Ingvar Eidhammer

Affiliation Department of Informatics, University of Bergen, Bergen, Norway

Inge Jonasen

Affiliation Department of Informatics, University of Bergen, Bergen, Norway

Susan Vanaken

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Terry Utterback

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Tamara V Feldblyum

Affiliation The Institute for Genomic Research, Rockville, Maryland, United States of America

Claire M Fraser

Affiliations The Institute for Genomic Research, Rockville, Maryland, United States of America, George Washington University Medical Center, Washington, District of Columbia, United States of America

Johan R Lillehaug

Affiliation Department of Molecular Biology, University of Bergen, Bergen, Norway

Jonathan A Eisen

Affiliations The Institute for Genomic Research, Rockville, Maryland, United States of America, Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

NW, CMF, JRL, and JAE conceived and designed the experiments. ØL, LB, HK, GD, LJ, DS, KK, ML, SV, TU, and TVF performed the experiments. NW, ØL, JS, LB, HK, ASD, GD, LJ, DS, KK, ML, KEN, BM, MW, JFH, ITP, DF, JR, HT, QR, TR, RD, RS, SLS, HBJ, NKB, WN, RJD, SV, TU, TVF, JRL, and JAE analyzed the data. SHG, IH, IE, and IJ contributed reagents/materials/analysis tools. NW, ØL, JS, LB, BM, JFH, ITP, DF, JR, TR, RD, RS, HBJ, NKB, CMF, JRL, and JAE wrote the paper.