About the Authors

Karl Simin

Affiliation Department of Genetics, Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Hua Wu

Address address: Phenomix Corporation, La Jolla, California, United States of America

Affiliation Department of Genetics, Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Lucy Lu

Affiliation Department of Genetics, Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Dan Pinkel

Affiliation Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, United States of America

Donna Albertson

Affiliation Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, United States of America

Robert D Cardiff

Affiliation Center for Comparative Medicine, University of California, Davis, Davis, California, United States of America

Terry Van Dyke

To whom correspondence should be addressed. E-mail: tvdlab@med.unc.edu

Affiliation Department of Genetics, Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

KS, HW, and TVD conceived and designed the experiments. KS, HW, and LL performed the experiments. KS, HW, RDC, and TVD analyzed the data. DP and DA contributed reagents/materials/analysis tools. KS and TVD wrote the paper.