About the Authors

Iben Lundgaard

Contributed equally to this work with: Iben Lundgaard, Aryna Luzhynskaya, John H. Stockley

Current address: Center for Translational Neuromedicine, Department of Neurosurgery, University of Rochester, Rochester, New York, United States of America.

Affiliation Wellcome Trust–Medical Research Council (MRC) Stem Cell Institute, John van Geest Centre for Brain Repair, and Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Aryna Luzhynskaya

Contributed equally to this work with: Iben Lundgaard, Aryna Luzhynskaya, John H. Stockley

Affiliation Wellcome Trust–Medical Research Council (MRC) Stem Cell Institute, John van Geest Centre for Brain Repair, and Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

John H. Stockley

Contributed equally to this work with: Iben Lundgaard, Aryna Luzhynskaya, John H. Stockley

Affiliation Wellcome Trust–Medical Research Council (MRC) Stem Cell Institute, John van Geest Centre for Brain Repair, and Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Zhen Wang

Current address: Institut de Biologie de l'Ecole Normale Supérieure Génomique Fonctionnelle–CNRS, Paris, France.

Affiliation Department of Pathology, University of Cambridge, Cambridge, United Kingdom

Kimberley A. Evans

Affiliation Wellcome Trust–Medical Research Council (MRC) Stem Cell Institute, John van Geest Centre for Brain Repair, and Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Matthew Swire

Affiliation MRC Centre for Regenerative Medicine, Centre for Multiple Sclerosis Research, University of Edinburgh, Edinburgh, United Kingdom

Katrin Volbracht

Affiliation Wellcome Trust–Medical Research Council (MRC) Stem Cell Institute, John van Geest Centre for Brain Repair, and Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Hélène O. B. Gautier

Affiliation Wellcome Trust–Medical Research Council (MRC) Stem Cell Institute, John van Geest Centre for Brain Repair, and Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Robin J. M. Franklin

Affiliation Wellcome Trust–Medical Research Council (MRC) Stem Cell Institute, John van Geest Centre for Brain Repair, and Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Charles ffrench-Constant

Affiliation MRC Centre for Regenerative Medicine, Centre for Multiple Sclerosis Research, University of Edinburgh, Edinburgh, United Kingdom

David Attwell

Affiliation Department of Neuroscience, Physiology & Pharmacology, University College London, London, United Kingdom

Ragnhildur T. Káradóttir

rk385@cam.ac.uk

Affiliation Wellcome Trust–Medical Research Council (MRC) Stem Cell Institute, John van Geest Centre for Brain Repair, and Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: RTK DA Cff IL AL JHS. Performed the experiments: IL AL JHS KAE MS KV ZW HOBG RTK. Analyzed the data: IL AL JHS KAE MS KV ZW HOBG DA RTK. Contributed reagents/materials/analysis tools: Cff DA RTK. Wrote the paper: IL AL RJMF Cff DA RTK.