About the Authors

Edward Yeh

Contributed equally to this work with: Edward Yeh, Sharon Ng, Mi Zhang

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

Sharon Ng

Contributed equally to this work with: Edward Yeh, Sharon Ng, Mi Zhang

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada , Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Mi Zhang

Contributed equally to this work with: Edward Yeh, Sharon Ng, Mi Zhang

Affiliation Division of Biology, University of California San Diego, San Diego, California, United States of America

Magali Bouhours

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

Ying Wang

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

Min Wang

Affiliation Department of Neuroscience, Centre for Addiction and Mental Health, Clarke Division, University of Toronto, Toronto, Ontario, Canada

Wesley Hung

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

Kyota Aoyagi

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

Katya Melnik-Martinez

Affiliation Division of Biology, University of California San Diego, San Diego, California, United States of America

Michelle Li

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada , Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Fang Liu

Affiliation Department of Neuroscience, Centre for Addiction and Mental Health, Clarke Division, University of Toronto, Toronto, Ontario, Canada

William R Schafer

Affiliations Division of Biology, University of California San Diego, San Diego, California, United States of America , Cell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom

Mei Zhen

To whom correspondence should be addressed. E-mail: zhen@mshri.on.ca

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada , Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

E. Yeh conceived and designed the experiments, performed the experiments, and analyzed the data. S. Ng and M. Zhang performed the experiments, analyzed the data, and contributed reagents/materials/analysis tools. M. Bouhours performed the experiments, analyzed the data, and wrote the paper. Y. Wang, K. Melnick-Martinez, and M. Li performed the experiments. M. Wang, W. Hung, and K. Aoyagi performed the experiments and analyzed the data. F. Liu conceived and designed the experiments. W. R. Schafer conceived and designed the experiments and wrote the paper. M. Zhen conceived and designed the experiments, performed the experiments, analyzed the data, and wrote the paper.