About the Authors
- Daniel A Kraut
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Affiliation Department of Biochemistry, Stanford University, Stanford, California, United States of America
- Paul A Sigala
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Affiliation Department of Biochemistry, Stanford University, Stanford, California, United States of America
- Brandon Pybus
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Affiliation Department of Biochemistry, Brandeis University, Waltham, Massachusetts, United States of America
- Corey W Liu
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Affiliation Stanford Magnetic Resonance Laboratory, Stanford University, Stanford, California, United States of America
- Dagmar Ringe
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Affiliation Department of Biochemistry, Brandeis University, Waltham, Massachusetts, United States of America
- Gregory A Petsko
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Affiliation Department of Biochemistry, Brandeis University, Waltham, Massachusetts, United States of America
- Daniel Herschlag
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*To whom correspondence should be addressed. E-mail: herschla@stanford.edu
Affiliation Department of Biochemistry, Stanford University, Stanford, California, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
DAK, PAS, and DH conceived and designed the experiments, BP performed X-ray crystallography experiments, PAS performed 1D 1H and 19F NMR experiments, PAS and CWL performed 2D NOESY NMR experiments, DAK carried out assay development and performed binding assays and ITC experiments. DAK, PAS, BP, CWL, DR, GAP, and DH analyzed the data. DAK, PAS, BP, CWL, DR, GAP, and DH wrote the paper.