Interaction Networks in Yeast Define and Enumerate the Signaling Steps of the Vertebrate Aryl Hydrocarbon Receptor

Guang Yao; Mark Craven; Norman Drinkwater; Christopher A Bradfield

doi:10.1371/journal.pbio.0020065

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Open Access

Peer-reviewed

Research Article

Interaction Networks in Yeast Define and Enumerate the Signaling Steps of the Vertebrate Aryl Hydrocarbon Receptor

Guang Yao,

Affiliation McArdle Laboratory for Cancer Research, University of Wisconsin Medical School, Madison, Wisconsin, United States of America
⨯
Mark Craven,

Affiliation Department of Biostatistics and Medical Informatics, University of Wisconsin Medical School, Madison, Wisconsin, United States of America
⨯
Norman Drinkwater,

Affiliation McArdle Laboratory for Cancer Research, University of Wisconsin Medical School, Madison, Wisconsin, United States of America
⨯
Christopher A Bradfield

Affiliation McArdle Laboratory for Cancer Research, University of Wisconsin Medical School, Madison, Wisconsin, United States of America
⨯

Interaction Networks in Yeast Define and Enumerate the Signaling Steps of the Vertebrate Aryl Hydrocarbon Receptor

Guang Yao,
Mark Craven,
Norman Drinkwater,
Christopher A Bradfield

Published: March 16, 2004
https://doi.org/10.1371/journal.pbio.0020065

About the Authors

Guang Yao: Affiliation McArdle Laboratory for Cancer Research, University of Wisconsin Medical School, Madison, Wisconsin, United States of America
Mark Craven: Affiliation Department of Biostatistics and Medical Informatics, University of Wisconsin Medical School, Madison, Wisconsin, United States of America
Norman Drinkwater: Affiliation McArdle Laboratory for Cancer Research, University of Wisconsin Medical School, Madison, Wisconsin, United States of America
Christopher A Bradfield: Affiliation McArdle Laboratory for Cancer Research, University of Wisconsin Medical School, Madison, Wisconsin, United States of America

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

GY and CAB conceived and designed the experiments. GY performed the experiments and analyzed the data. GY, MC, and ND contributed reagents/materials/analysis tools. GY and CAB wrote the paper.

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Yeast
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Saccharomyces cerevisiae
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Protein interaction networks
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Signaling networks
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Nuclear receptor signaling
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Pharmacology
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Plasmid construction
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Protein folding
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